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Author: Admin | 2025-04-28
HomeAllopurinol Generic name: allopurinol (oral/injection) [ AL-oh-PURE-i-nol ]Brand names: Zyloprim, Lopurin, AloprimDosage forms: intravenous powder for injection (500 mg), oral tablet (100 mg; 200 mg; 300 mg)Drug classes: Antigout agents, Antihyperuricemic agents UsesWarningsBefore takingDosageSide effectsInteractions What is allopurinol?Allopurinol belongs to a class of medications called xanthine oxidase inhibitors. It works by reducing the production of uric acid in the body. High levels of uric acid may cause gout attacks or kidney stones.Allopurinol is used to treat gout (a type of arthritis in which uric acid, a naturally occurring substance in the body, builds up in the joints and causes sudden attacks of redness, swelling, pain, and heat in one or more joints). Allopurinol is used to prevent gout attacks, not to treat them once they occur. Allopurinol does not need to be stopped during an acute flare.Allopurinol is also used to treat high levels of uric acid that builds up in the blood as tumors break down in people with certain types of cancer who are being treated with chemotherapy medications. It is also used to treat kidney stones that have come back in people who have high levels of uric acid in their urine.WarningsYou should not use this medicine if you have ever had an allergic reaction to allopurinol.Allopurinol can lower blood cells that help your body fight infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. Your blood may need to be tested often. Visit your doctor regularly.In rare cases, allopurinol may cause a severe allergic reaction. Stop taking this medicine and call your doctor right away if you have painful urination, blood in your urine, burning in your eyes, swelling in your face or throat, skin redness or a rash that spreads and causes blistering and peeling.Avoid drinking alcohol. It can make your condition worse. Allopurinol may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.Before taking this medicineYou should not use allopurinol if you are allergic to it.To make sure this medicine is safe for you, tell your doctor if you have ever had:diabetes;congestive heart failure;high blood pressure;if you are receiving chemotherapy;if you have a gene variation called HLA-B*58:01 allele (your doctor can test you for this);liver disease; orkidney disease.Allopurinol may harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.Do not breastfeed while using this medicine, and for at least 1 week after your last dose.How should I use allopurinol?Take allopurinol exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.Take the tablets with a full glass of water. To reduce your risk of kidney stones, drink 8 to 10 full glasses of fluid every day, unless your doctor tells you otherwise.Take with food if allopurinol tablets upsets your stomach.Allopurinol injection is injected into a vein by
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