Gene, That is a large dosage change for the Levodopa. There is a conversion chart when switching from Sinemet to Rytary, which will tell you
If the patient is on Rytary capsule at home and has a NG tube (Rytary cannot be crushed), then please switch to the equivalent dose of Sinemet 25/100 that can be given via tube. [Rytary to Sinemet 25/100 conversion formula: total daily dose of Rytary divided by 2= total daily dose of Sinemet 25/100; divide the total daily dose in 3-4 times a day]
If my doctor switches me to Rytary, is there a dosing conversion tool or calculator? To find out how Rytary compares with Sinemet, read this
In clinical trials (1,2), patients on carbidopa/levodopda IR (Sinemet) were converted to Rytary according to a dosage conversion table that is
Conversion from IMMEDIATE-RELEASE carbidopa-levodopa to RYTARY Sinemet, Rytary, Sinemet CR, Crexont, 3 more. Related treatment
Dosages of Rytary and Sinemet are not interchangeable. Available manufacturer guidance provides information on conversions FROM Sinemet TO Rytary (see
Sinemet Sinemet CR Stalevo Symmetrel. Drug Summary. What Is Rytary? Rytary RYTARY compared to approximately 3.2 for immediate-release levodopa.
Rytary; Sinemet ; Sinemet ; Sinemet ; Sinemet CR. Canadian Brand Name. Sinemet ; Sinemet ; Sinemet ; Sinemet CR ; Sinemet
Real-World Experience with Carbidopa-Levodopa Extended-Release Capsules (Rytary): Results of a Nationwide Dose Conversion Survey (Sinemet), sustained
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