Maximum dose: 800mg/day. Reduce dose in patients with renal impairment Allopurinol dosage Allopurinol Gout treatment. Suggestions.
doses in patients with renal insufficiency because of the risk of allopurinol hypersensitivity. Gradual allopurinol dose escalation, in
Allopurinol. Allopurinol has a renally excreted active metabolite that accumulates in renal impairment and may cause adverse effects if the dose is not adjusted
Renal-dosing of allopurinol compounds the poor management of gout and adds to the perception that allopurinol may be detrimental for renal
Alternatively, colchicine Lowering the starting dose of allopurinol appropriate to the level of renal function reduces the risk of allopurinol.
This article stresses the importance of renal insufficiency as a risk factor in allopurinol hypersensitivity, and the importance of reducing allopurinol dose in
Maximum dose: 800mg/day. Reduce dose in patients with renal impairment. Closely Allopurinol dosage Allopurinol Gout treatment. Suggestions.
Lack of effect of hydrochlorothiazide and low-dose aspirin on the renal allopurinol, are unlikely to alter the hypouricaemic effect of allopURinol.
4 Allopurinol dose needs to be adjusted in renal failure. Maximum daily dose of allopurinol is 800 mg/day. Dose adjustments may be necessary if allopurinol
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