The bioavailability of morphine is %. There is significant first-pass metabolism, therefore oral doses are 6 times larger than parenteral doses to achieve the same effect. Morphine reaches steady-state concentrations after hours. Parenteral morphine has a T max of 15 minutes and oral morphine has a T max of 90 minutes, with a C max
Morphine reaches steady-state concentrations after hours. 1 Parenteral morphine has a T max of 15 minutes and oral morphine has a T max of 90 minutes, with a C max of 283nmol/L. 7,8 The AUC of morphine is nmolh/L. 8. Volume of distribution
The bioavailability of morphine is %. There is significant first-pass metabolism, therefore oral doses are 6 times larger than parenteral doses to achieve the same effect. Morphine reaches steady-state concentrations after hours. Parenteral morphine has a T max of 15 minutes and oral morphine has a T max of 90 minutes, with a C max
The bioavailability of morphine is %. There is significant first-pass metabolism, therefore oral doses are 6 times larger than parenteral doses to achieve the same effect. Morphine reaches steady-state concentrations after hours. Parenteral morphine has a T max of 15 minutes and oral morphine has a T max of 90 minutes, with a C max
Morphine reaches steady-state concentrations after hours. 1 Parenteral morphine has a T max of 15 minutes and oral morphine has a T max of 90 minutes, with a C max of 283nmol/L. 7,8 The AUC of morphine is nmolh/L. 8
The bioavailability of morphine is %. There is significant first-pass metabolism, therefore oral doses are 6 times larger than parenteral doses to achieve the same effect. Morphine reaches steady-state concentrations after hours. Parenteral morphine has a T max of 15 minutes and oral morphine has a T max of 90 minutes, with a C max
Morphine reaches steady-state concentrations after hours. 1 Parenteral morphine has a T max of 15 minutes and oral morphine has a T max of 90 minutes, with a C max of 283nmol/L. 7,8 The AUC of morphine is nmolh/L. 8
Morphine (Oramorph) PRN, max hourly. You wish to prescribe One sixth of this is the 4hrly dose – prescribe 5mg Morphine subcutaneously PRN, max hourly.
Morphine reaches steady-state concentrations after hours. 1 Parenteral morphine has a T max of 15 minutes and oral morphine has a T max of 90 minutes, with a C max of 283nmol/L. 7,8 The AUC of morphine is nmolh/L. 8. Volume of distribution
Regards, Jack