Pegfilgrastim vs filgrastim

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Actual: Releuko (filgrastim-ayow) Zarxio (filgrastim-sndz) Biosimilars to Neulasta include: Fulphila (pegfilgrastim-jmdb) Fylnetra (pegfilgrastim-pbbk) Nyvepria (pegfilgrastim-apgf) Stimufend (pegfilgrastim-fpgk) Udenyca (pegfilgrastim-cbvq) Ziextenzo (pegfilgrastim-bmez) Though not a biosimilar, Neulasta also has another product called Neulasta On
4.9 rating 2025-04-24
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by SH Schmidt 2024With the approval of filgrastim-sndz (Zarxio) and TBO-filgrastim (Granix), drug cost has decreased compared to pegfilgrastim (Neulasta) and filgrastim (

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In Skarlos et al, a post-hoc non-randomized subgroup analysis evaluating filgrastim versus pegfilgrastim, a significantly higher incidence of FN was observed in patients treated with pegfilgrastim compared with those receiving filgrastim (13% vs. 1% for pegfilgrastim vs. filgrastim, respectively) .

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Due to a longer half-life and slower elimination rate than filgrastim, pegfilgrastim requires less frequent dosing than filgrastim; however, pegfilgrastim has

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Use of pegfilgrastim vs short-acting G-CSF. Clinical trial data suggest a similar efficacy and safety profile with pegfilgrastim and 11 days filgrastim. 1 If 11 days filgrastim is not utilized, pegfilgrastim should be given in preference to a reduced duration of daily filgrastim (consensus reached (91%); evidence level I).

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filgrastim (Granix) and sargramostim (Leukine). Filgrastim and pegfilgrastim products are recombinant granulocyte colony- stimulating

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Other treatment-related adverse events including arthralgia (1.7 vs 6%), back pain (6.9 vs 3%) and headache (1.7 vs 6%) were reported for pegfilgrastim vs filgrastim.

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by P Berto 2024pegfilgrastim versus daily filgrastim in patients receiving myelosuppressive chemotherapy. Comparison of pegfilgrastim with filgrastim on febrile

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Results: Medical records of 624 pts from 34 sites receiving pegfilgrastim or filgrastim have been abstracted to date. Pegfilgrastim was initiated in 351(56%) pts and filgrastim was initiated in 273 (44%) pts. Of the 624 pts, 120 (19%) received both pegfilgrastim and filgrastim (no pt used both products in the same cycle).

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Neulasta (pegfilgrastim); Udenyca (pegfilgrastim-cbqv). Short-acting CSFs. Granix (tbo-filgrastim); Zarxio

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