Understanding the interactions of amlodipine with other medications is integral to ensuring its safe use. Amlodipine’s interactions primarily involve drugs that impact its metabolism or those that might enhance its effects. a. Metabolic Interactions. Amlodipine is metabolized in the liver, primarily through the cytochrome P450 3A4 enzyme.
amlodipine to patients diagnosed with hypertension, amlodipine causes The metabolism of Amlodipine can be increased when combined with Vitamin E.
Amlodipine Metabolism in Human Liver Microsomes and Roles of CYP3A4/5 in the Dihydropyridine Dehydrogenation. Drug Metabolism and Disposition.
amlodipine or these drugs. Dosages of similarly metabolized drugs Amlodipine is a member of the dihydropyridine class of calcium antagonists.
Amlodipine is mainly metabolized by cytochrome P450 (CYP) 3A4, whereas losartan is metabolized by CYP2C9 and CYP3A4. The potential pharmacokinetic interactions between amlodipine and losartan were assessed. An open‐label, three‐period, fixed‐ sequence trial was conducted. Amlodipine, losartan and combined amlodipine and
amlodipine to patients diagnosed with hypertension, amlodipine causes The metabolism of Sildenafil can be decreased when combined with Amlodipine.
Since the heart rate remains stable during amlodipine administration, the of Amlodipine. Clevidipine, The metabolism of Amlodipine can be increased when
Amlodipine, The metabolism of Acetylsalicylic acid can be decreased when combined with Amlodipine. Ammonium chloride, The serum concentration of
The metabolism of Acenocoumarol can be decreased when combined with Amlodipine. Acetaminophen, The metabolism of Amlodipine can be increased when combined
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